Anaplastic Transformation of Differentiated Thyroid Carcinoma

Gamal Khairy

Abstract


Abstract: Anaplastic thyroid cancer (ATC) is one of the most aggressive malignancies that arise from transformation of preexisting
differentiated thyroid cancer (DTC). However, the carcinogenic mechanism of anaplastic transformation remains
unclear. We describe a case for huge goiter diagnosed as papillary thyroid carcinoma, which underwent thyroidectomy. The
final histology showed anaplastic transformation. The clinical and possible etiological aspects are discussed.
Keywords: anaplastic, thyroid cancer, transformation

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International Journal of Health Sciences is a scientific publications by Qassim University, Kingdom of Saudi Arabia.